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(2) efforts to develop drugs to rid neurons of amyloid plaque buildup have thus far failed to improve cognitive processing

331 Notably, 12 months after splenectomy plus pericardial devascularization in chronic hepatitis B cirrhosis patients, gut flora composition restored to near healthy control levels, and liver function, intestinal permeability, and inflammation levels improved compared to pre-surgery, indicating that the improvement in liver function and intestinal permeability after splenectomy plus pericardial devascularization may be related to gut flora recovery